« Back
Home /
ziresovir

ziresovir

Item no.	V5311-50mg
Manufacturer	InvivoChem LLC
CASRN	1422500-60-4
Amount	50 mg
Quantity options	100 mg 10 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5311CAS #:1422500-60-4Purity >=98% Description: Ziresovir (known also as AK-0529; RO-0529) is a selective and orally bioavailable inhibitor of respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein with EC50 of 3 nM. Ziresovir is currently in phase 2 clinical trials. RO-0529 demonstrates single-digit nM EC50 potency against laboratory strains, as well as clinical isolates of RSV in cellular assays, and more than one log viral load reduction in BALB/c mouse model of RSV viral infection. RO-0529 was proven to be a specific RSV F protein inhibitor by identification of drug resistant mutations of D486N, D489V, and D489Y in RSV F protein and the inhibition of RSV F protein-induced cell?cell fusion in cellular assays. References: Nat Chem Biol. 2009 Feb; 5(2):108-17. Related CAS: 2066577-28-2 (hydrate); 2066577-29-3 (acetate); 2066577-30-6 (maleate)
	Name: Ziresovir CAS#: 1422500-60-4 (free base) Chemical Formula: C22H25N5O3S Exact Mass: 439.1678 Molecular Weight: 439.53 Elemental Analysis: C, 60.12; H, 5.73; N, 15.93; O, 10.92; S, 7.29
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: RO-0529; RO0529; RO 0529; AK0529; AK-0529; AK 0529; Chemical Name: N-[(3-aminooxetan-3-yl)methyl]-2-(1, 1-dioxido-2, 3-dihydro-1, 4-benzothiazepin-4(5H)-yl)-6-methylquinazolin-4-amine InChi Key: GAAICKUTDBZCMT-UHFFFAOYSA-N InChi Code: InChI=1S/C22H25N5O3S/c1-15-6-7-18-17(10-15)20(24-12-22(23)13-30-14-22)26-21(25-18)27-8-9-31(28, 29)19-5-3-2-4-16(19)11-27/h2-7, 10H, 8-9, 11-14, 23H2, 1H3, (H, 24, 25, 26) SMILES Code: CC1=CC2=C(NCC3(N)COC3)N=C(N(CC4=CC=CC=C45)CCS5(=O)=O)N=C2C=C1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50 mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 13 days

Compare

Add to wishlist

Get an offer