Comparison

aa-115

Item no. V5403-25mg
Manufacturer InvivoChem LLC
CASRN 1818393-16-6
Amount 25 mg
Quantity options 1 mg 250 mg 500 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V5403CAS #:1818393-16-6Purity >=98%

Description: AA-115, formerly known as APG-115, is a novel, potent, orally bioactive and chemically stable and efficacious MDM2 inhibitor, which has entered clinical trials for cancer treatment. AA-115 has a very high affinity to MDM2 (Ki < 1 nM), potent cellular activity, and an excellent orally bioavailable pharmacokinetic profile. Compound 60 is capable of achieving complete and longlasting tumor regression in vivo and is currently in phase I clinical trials for cancer treatment.

References: J Med Chem. 2017 Apr 13; 60(7): 2819–2839.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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