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bms-906024

bms-906024

Item no.	V5895-250mg
Manufacturer	InvivoChem LLC
CASRN	1401066-79-2
Amount	250 mg
Quantity options	100 mg 1 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5895CAS #:1401066-79-2Purity >=98% Description: BMS-906024 is a novel, potent, selective and orally bioavailable Notch receptor inhibitor. Cancers have a tendency to relapse or to become resistant to treatments that once worked. A family of proteins called Notch is implicated in that resistance and in cancer progression more generally. BMS-906024 is in Phase I clinical trials, both alone and in combination with other agents. Patients with colon, lung, breast, and other cancers are receiving intravenous doses of the compound to determine its safety and optimum dose ranges. References: 1. MorganKM, et al. Gamma Secretase Inhibition by BMS-906024 Enhances Efficacyof Paclitaxel in Lung Adenocarcinoma. Mol Cancer Ther. 2017Dec; 16(12):2759-2769. 2. GavaiAV, et al. Discovery of Clinical Candidate BMS-906024: A PotentPan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors. ACSMed Chem Lett. 2015 Mar 11; 6(5):523-7.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 10/2/2025

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