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bms986126

bms986126

Item no.	V6318-50mg
Manufacturer	InvivoChem LLC
CASRN	1610017-20-3
Amount	50 mg
Quantity options	100 mg 250 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V6318CAS #:1610017-20-3Purity >=98% Description: BMS-986126 is a novel and potent IRAK4 Inhibitor that is able to attenuate disease in murine Lupus models and displays seroid sparing activity. BMS-986126 inhibited TLR7- and TLR9-dependent responses using cells derived from lupus patients, suggesting that inhibition of IRAK4 has the potential for therapeutic benefit in treating lupus. References: Ruepp S, Janovitz E, Brodie T, White R, Santella J, Hynes J, Carman J, Pan D, Wu Y, Hanumegowda U, Gemzik B, Megill J, DiPiero J, Drexler D, Su CC, Hageman M.Assessing the risk of drug crystallization in vivo. J Pharmacol Toxicol Methods.2019 Mar - Apr; 96:1-8. doi: 10.1016/j.vascn.2018.12.003. Epub 2018 Dec 13. PubMedPMID: 30553974.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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