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Naloxegol Oxalate

Naloxegol Oxalate

Item no.	V9135-100mg
Manufacturer	InvivoChem LLC
CASRN	1354744-91-4
Amount	100 mg
Quantity options	10 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V9135CAS #:1354744-91-4Purity >=98% Description: Naloxegol, formerly known as and NKTR-118 and AZ-13337019, is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation. It was approved in 2014 in adult patients with chronic, non-cancer pain. Chemically, naloxegol is a pegylated (polyethylene glycol-modified) analogue of alpha-naloxol. Specifically, the 5-alpha-hydroxyl group of alpha-naloxol is connected via an ether linkage to the free hydroxyl group of a monomethoxy-terminated n=7 oligomer of PEG. References: Al-Huniti N. Reply to: Letter to the Editor 'Effect of Quinidine, a Strong P-Glycoprotein Inhibitor, on the Pharmacokinetics and Central Nervous System Distribution of Naloxegol'. J Clin Pharmacol. 2016 Apr; 56(4):508. doi: 10.1002/jcph.674. PubMed PMID: 26954553.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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