Comparison

azd4573-hcl

Item no. V9625-100mg
Manufacturer InvivoChem LLC
CASRN Unknown for AZD4573 HCl
Amount 100 mg
Quantity options 250 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V9625CAS #:Unknown for AZD4573 HClPurity >=98%

Description: AZD4573 HCl is a novel potent and short acting inhibitor of serine/threonine CDK9 (cyclin-dependent kinase 9) with IC50 of< 0.004 uM and with fast-off binding kinetics (t1/2 = 16 min) as well as high selectivity versus other kinases, including other CDK family kinases. AZD4573 binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb-mediated activation of RNA Pol II, leading to the inhibition of gene transcription of various anti-apoptotic proteins.

Description:

References: http://cancerres.aacrjournals.org/content/78/13_Supplement/310; http://cancerres.aacrjournals.org/content/78/13_Supplement/1650

References:


Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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