Comparison

sri37892

Item no. V9832-250mg
Manufacturer InvivoChem LLC
CASRN 1030769-75-5
Amount 250 mg
Quantity options 100 mg 1 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V9832CAS #:1030769-75-5Purity >=98%

Description: SRI37892 is a frizzled-7 (Fzd7) inhibitor which inhibits LRP6 phosphorylation, downregulates the level of cytosolic free beta-catenin, and functionally represses breast cancer cell viability and colony formation. SRI37892 targets the transmembrane domain of FZD7, thereby blocking the WNT signal transmission.

References: Zhang W, Lu W, Ananthan S, Suto MJ, Li Y. Discovery of novel frizzled-7 inhibitors by targeting the receptor's transmembrane domain. Oncotarget. 2017 Sep 6; 8(53):91459-91470. doi: 10.18632/oncotarget.20665. eCollection 2017 Oct 31. PubMed PMID: 29207657; PubMed Central PMCID: PMC5710937.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 mg
Available: In stock
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