« Back
Home /
YKL-5-124

YKL-5-124

Item no.	M10734-5mg
Manufacturer	AbMole
CASRN	1957203-01-8
Amount	5mg
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Purity	>98%
Formula	C28H33N7O3
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Target Information	CDK
Molecular Weight	515, 61
Solubility	DMSO ≥ 60 mg/mL
Bioactivity information	YKL-5-124 is a potent, selective, irreversible COVALENT inhibitor of CDK7 and CDK7/Mat1/CycH IC50 53.5 nM and 9.7 nM, respectively. YKL-5-124 is more than 100 times more selective to CDK7 than CDK9 and CDK2 and is inactive to CDK12 and CDK13. YKL-5-124 induces intense cell cycle arrest and inhibits E2F-driven gene expression with little effect on RNA polymerase II phosphorylation status.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5mg

available

Delivery expected until 9/4/2025

Compare

Add to wishlist

Get an offer

Request delivery time