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GFB-8438

GFB-8438

Item no.	M10927-25mg
Manufacturer	AbMole
CASRN	2304549-73-1
Amount	25mg
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Purity	>98%
Formula	C16H14ClF3N4O2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Target Information	TRP Channel
Molecular Weight	386, 76
Solubility	DMSO ≥ 60 mg/mL
Bioactivity information	GFB-8438 is a potent subtype selective TRPC5 inhibitor against hTRPC5 and hTRPC4 IC50 0.18 and 0.29 μM, respectively. GFB-8438 has good selectivity for TRPC6, other members of the TRP family, NaV1.5, and limited activity against hERG channels. Protective effect of GFB-8438 on mouse podocytes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 10/23/2025

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