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Anti-Butyryllysine Antibody Conjugated Agarose Beads

Anti-Butyryllysine Antibody Conjugated Agarose Beads

Item no.	PTM-302
Manufacturer	PTM Biolabs
Amount	500 ul
Category	Reagents & Chemicals Nanoparticles Beads & Resins
Type	Antibody Conjugated Beads
Format	Liquid
Applications	IA
Specific against	other
Isotype	IgG
Conjugate/Tag	Agarose
Dry ice	Yes
Citations	Lu Yue, et al. Dynamics and functional interplay of histone lysine butyrylation, crotonylation, and acetylation in rice under starvation and submergence. GENOME BIOLOGY, 2018. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1533-y.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	41105507
Alias	Kbu
Shipping Condition	Dry ice
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Applications	IAP
Manufacturer - Category	Pan PTM Antibodies
Shipping Temperature	Cold packs / dry ice
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight	Multiple
Stability	Stable for 12 months from date of receipt.
Manufacturer - Research Area	Post-Translational Modificaiton
Manufacturer - Reactivity	All
Product description	Lysine butyrylation is a newly identified reversible modification controlling protein activity. With integrated proteomic approaches and biochemistry analysis, lysine butyrylation has been well demonstrated in both prokaryotes and eukaryotes in wide ranges of proteins including histones and non-histone substrates. Lysine butyrylation may play a vital role in epigenetic modulation by impacting chromatin dynamics and lasticity, DNA transcriptional regulation and tumorigenesis, etc.
Manufacturer - Specificity	With the immobilization of highly specific anti-butyryllysine antibody, the Anti-Butyryllysine Antibody Conjugated Agarose Beads selectively capture peptides/proteins bearing butyryllysine residues, but do not cross-reactwith the peptides/proteins bearing other structurally similar modified residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine butyrylation.
Formula	Antibody conjugated agarose beads are supplied as a 50% slurry containing 66% glycerol and 4 mg/ml immobilized antibody.
PTM	Butyryl
Modification Site	Lys
Immunogen	Butyrylated lysine peptides
Clonality	Polyclonal/Monoclonal
Background	Lysine butyrylation is a newly identified reversible modification controlling protein activity. With integrated proteomic approaches and biochemistry analysis, lysine butyrylation has been well demonstrated in both prokaryotes and eukaryotes in wide ranges of proteins including histones and non-histone substrates. Lysine butyrylation may play a vital role in epigenetic modulation by impacting chromatin dynamics and lasticity, DNA transcriptional regulation and tumorigenesis, etc.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ul

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Delivery expected until 11/27/2025

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