NT-3

Item no.	RLT-M10-232
Manufacturer	ReliaTech
Amount	10ug
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Monkey (Cynomolgus, Simian), Bovine, Hamster, Chicken (Gallus gallus domesticus), Dog (Canine, Canis lupus familiaris), Frog
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Ntf3, Nt3, Ntf-3, AI316846, AI835689
Available
NCBI Gene ID	18205
Uniprot	P20181
Biological Activity	The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
Description	NT3 a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	120
Molecular Weight	13.6 kDa
mRNA RefSeq	NM_008742.3
Protein RefSeq	NP_032768.1
Protein Sequence	MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	Ntf3; Nt3; Ntf-3; AI316846; AI835689
Uniprot ID	P20181

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