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FGF acidic

FGF acidic

Item no.	RLT-100-016S
Manufacturer	ReliaTech
Amount	10ug
Category	Oncology Neuroscience Metabolism Regulation of Appetite Neural Adhesion Molecules By Cell Type Carcinoma Hematology Leukemia Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines By Organ Bladder Cancer
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Bovine, Hamster
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	FGF2, BFGF, FGFB, HBGF-2
Available
NCBI Gene ID	2246
Uniprot	P05230
Biological Activity	Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is = 10 ng/ml. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is = 0.5 ng/ml in the presence of 10 µg/ml heparin.
Description	FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 15.8 kDa protein consisting of 140 amino acid residues.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	141
Molecular Weight	15.8 kDa
mRNA RefSeq	NM_000800.4
Protein RefSeq	NP_000791.1
Protein Sequence	MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Purity Confirmation	> 95% by SDS-PAGE & HPLC analyses
Synonyms	FGF2; BFGF; FGFB; HBGF-2
Uniprot ID	P05230

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Amount: 10ug

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Delivery expected until 8/21/2025

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