Comparison

MDC (67 aa) European Partner

Item no. RLT-100-069S
Manufacturer ReliaTech
Amount 5ug
Category
Type Cytokines and Growth Factors
Format Lyophilized
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Hamster
Host E.coli
ECLASS 10.1 42030690
ECLASS 11.0 42030690
UNSPSC 12352202
Alias ADAM11, MDC
Available
NCBI Gene ID
4185
Uniprot
O75078
Biological Activity
Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml.
Description
MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant human MDC is an 8.0 kDa protein containing 67 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Endotoxin Levels
< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]
67
Molecular Weight
8.0 kDa
mRNA RefSeq
NM_002390
Protein RefSeq
NP_002381
Protein Sequence
YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ
Purity Confirmation
> 98% by SDS-PAGE & HPLC analyses
Synonyms
ADAM11; MDC
Uniprot ID
O75078

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5ug
Available: In stock
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