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JE (MCP-1, CCL2)

JE (MCP-1, CCL2)

Item no.	RLT-M10-026
Manufacturer	ReliaTech
Amount	10ug
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Monkey (Cynomolgus, Simian), Rabbit (Oryctolagus cuniculus)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Ccl2, JE, HC11, MCAF, MCP1, MCP-1, Scya2, Sigje, SMC-CF, AI323594
Available
NCBI Gene ID	20296
Uniprot	P10148
Biological Activity	Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.
Description	The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	125
Molecular Weight	13.8 kDa
mRNA RefSeq	NM_011333.3
Protein RefSeq	NP_035463.1
Protein Sequence	QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	Ccl2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594
Uniprot ID	P10148

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10ug

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Delivery expected until 8/21/2025

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