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IFN-lambda1 (IL-29)

IFN-lambda1 (IL-29)

Item no.	RLT-100-193S
Manufacturer	ReliaTech
Amount	5ug
Category	Oncology By Cell Type Blastoma Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	IL29, IFNL1, IL-29, IL-29, IL-28A, IL-28B
Available
NCBI Gene ID	282618
Uniprot	Q8IU54
Biological Activity	Determined by its ability to activate STAT phosphorylation in an ISRE Luciferase Reporter Assay using human colon carcinoma COLO205 cells. The expected ED50 is 0.2-0.5 ng/ml.
Description	IFN lambda-1, -2, and -3 are distantly related to the IL-10 family and interferons. All three IFN-lambdas use a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I interferons (Kotenko, SV. et al. Nat Immunology 2003 [1] p. 69-77). Recombinant human IFN-lambda 1 is a 19.8 kDa protein containing 178 amino acid residues.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	178
Molecular Weight	19.8 kDa
mRNA RefSeq	NM_172140.1
Protein RefSeq	NP_742152.1
Protein Sequence	PTSKPTTTGK GCHIGRFKSL SPQELASFKK ARDALEESLK LKNWSCSSPV FPGNWDLRLL QVRERPVALE AELALTLKVL EAAAGPALED VLDQPLHTLH HILSQLQACI QPQPTAGPRP RGRLHHWLHR LQEAPKKESA GCLEASVTFN LFRLLTRDLK YVADGNLCLR TSTHPEST
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	IL29; IFNL1; IL-29; IL-29, IL-28A; IL-28B
Uniprot ID	Q8IU54

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Amount: 5ug

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Delivery expected until 8/21/2025

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