NT-4

Item no.	RLT-100-087S
Manufacturer	ReliaTech
Amount	2ug
Category	Neuroscience Targets for Rodent Neurosciences Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Frog
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	NTF4, NT4, NT5, NT-4, NT-5, NTF5, GLC10, GLC1O, NT-4/5
Available
NCBI Gene ID	4909
Uniprot	P34130
Biological Activity	Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
Description	NT-4 is a neurotrophic factor structurally related to ß-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	130
Molecular Weight	14 kDa
mRNA RefSeq	NM_006179.4
Protein RefSeq	NP_006170.1
Protein Sequence	GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	NTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5
Uniprot ID	P34130

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