FGF-18

Item no.	RLT-100-025
Manufacturer	ReliaTech
Amount	25ug
Category	Oncology Neuroscience Neural Signaling By Cell Type Carcinoma Hematology Myeloma Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	FGF18, ZFGF5, FGF-18
Available
NCBI Gene ID	8817
Uniprot	O76093
Biological Activity	The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is = 0.5 ng/ml (= 2 x 106 units/mg).
Description	FGF-18 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-18 is an essential regulator of long bone and calvarial development. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. Recombinant E.coli derived human FGF-18 is a 20.1 kDa protein consisting of 173 amino acid residues, resulting from c-terminal truncation of the full length protein.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	173
Molecular Weight	20.1 kDa
mRNA RefSeq	NM_003862
Protein RefSeq	NP_003853.1
Protein Sequence	AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR
Purity Confirmation	> 95% by SDS-PAGE & HPLC analyses
Synonyms	FGF18; ZFGF5; FGF-18
Uniprot ID	O76093

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