BMP-4

Item no.	RLT-100-326H
Manufacturer	ReliaTech
Amount	10ug
Category	Oncology Neuroscience Neural Signaling By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	HEK293
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	BMP4, ZYME, BMP2B, OFC11, BMP2B1, MCOPS6
Available
NCBI Gene ID	652
Uniprot	P12644
Biological Activity	The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).
Buffer	2XS PBS + 6% EtOH
Description	Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-ß superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
Length [aa]	113
Molecular Weight	34.0 kDa
mRNA RefSeq	NM_001202
Protein RefSeq	NP_001193
Protein Sequence	HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR
Purity Confirmation	>95% by SDS-PAGE
Stability And Storage	Lyophilized BMP4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BMP-4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Synonyms	BMP4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
Uniprot ID	P12644

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