EGF

Item no.	RLT-M10-003
Manufacturer	ReliaTech
Amount	500ug
Category	Oncology Neuroscience Neural Signaling By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Epidermal growth factor, Egf, AI790464
Available
NCBI Gene ID	13645
Uniprot	P01132
Biological Activity	The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is = 0.1 ng/ml, corresponding to a specific activity of = 1 x 107 units/mg.
Description	Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-a and VGF (vaccinia virus growth factor). Recombinant murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide-bonds.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	53
Molecular Weight	6.0 kDa
mRNA RefSeq	NM_010113.3
Protein RefSeq	NP_036974.1
Protein Sequence	NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	Epidermal growth factor; Egf; AI790464
Uniprot ID	P01132

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