IL-15

Item no.	RLT-R20-032S
Manufacturer	ReliaTech
Amount	2ug
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Il15, 19q11
Available
NCBI Gene ID	25670
Uniprot	P97604
Biological Activity	The ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 105 units/mg.
Description	IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	115
Molecular Weight	13.5 kDa
mRNA RefSeq	NM_013129
Protein RefSeq	NP_037261.1
Protein Sequence	MNWIDVRYDL EKIESLIQFI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VIESGCKECE ELEERNFTEF LQSFIHIVQM FINTS
Purity Confirmation	> 96% by SDS-PAGE & HPLC analyses
Synonyms	Il15; 19q11
Uniprot ID	P97604

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