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IGF-BP2

IGF-BP2

Item no.	RLT-100-198
Manufacturer	ReliaTech
Amount	20ug
Category	Oncology By Cell Type Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Insect Cells
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	IGFBP2, IBP2, IGF-BP53
Available
NCBI Gene ID	3485
Uniprot	P18065
Biological Activity	Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
Description	IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells. Recombinant human IGF-BP2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	289
Molecular Weight	31.5 kDa
mRNA RefSeq	NM_000597
Protein RefSeq	NP_000588.2
Protein Sequence	EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YN
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	IGFBP2; IBP2; IGF-BP53
Uniprot ID	P18065

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Delivery expected until 8/21/2025

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