IL-5

Manufacturer	ReliaTech
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Cytokines and Growth Factors
Specific against	Human, Mouse
Format	Lyophilized
Amount	25ug
Host	E.coli
Item no.	RLT-M10-046
Targets	IL5
eClass 6.1	32161000
eClass 9.0	42030690
Available
NCBI Gene ID	16191
Uniprot	P04401
Biological Activity	The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells and is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
Description	IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	113
Molecular Weight	26.2 kDa
mRNA RefSeq	NM_010558.1
Protein RefSeq	NP_034688.1
Protein Sequence	MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	Il5; Il-5; B-cell growth factor II Short name=BCGF-II Cytotoxic T-lymphocyte inducer Eosinophil differentiation factor T-cell replacing factor
Uniprot ID	P04401

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Amount: 25ug

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Delivery expected until 5/23/2024