BCMA

Item no.	RLT-100-131
Manufacturer	ReliaTech
Amount	20ug
Category	Oncology By Cell Type Hematology Myeloma Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	TNFRSF17, BCM, BCMA, CD269
Available
NCBI Gene ID	608
Uniprot	Q02223
Biological Activity	Data not available.
Description	BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain. Recombinant soluble BCMA is a 50 amino acid polypeptide (5.3 kDa) comprising the TNFR homologous region of the BCMA protein.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	50
Molecular Weight	5.3 kDa
mRNA RefSeq	NM_001192
Protein RefSeq	NP_001183
Protein Sequence	AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	TNFRSF17; BCM; BCMA; CD269
Uniprot ID	Q02223

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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