IL-19

Item no.	RLT-100-229S
Manufacturer	ReliaTech
Amount	2ug
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	IL19, MDA1, NG.1, ZMDA1, IL-10C
Available
NCBI Gene ID	29949
Uniprot	Q9UHD0
Biological Activity	Determined by its ability to activate STAT following receptor-ligand interaction.
Description	IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-alpha and induces apoptosis through TNF-alpha. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	153
Molecular Weight	17.9 kDa
mRNA RefSeq	NM_153758
Protein RefSeq	NP_715639.1
Protein Sequence	MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MSSA
Purity Confirmation	> 99% by SDS-PAGE & HPLC analysis
Synonyms	IL19; MDA1; NG.1; ZMDA1; IL-10C
Uniprot ID	Q9UHD0

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