Comparison

GLP-1 European Partner

Item no. RLT-100-339
Manufacturer ReliaTech
Amount 1000ug
Category
Type Cytokines and Growth Factors
Format Lyophilized
Specific against Human (Homo sapiens)
Host E.coli
ECLASS 10.1 42030690
ECLASS 11.0 42030690
UNSPSC 12352202
Alias GLP1, GLP2, GRPP
Available
NCBI Gene ID
2641
Uniprot
P01275
Biological Activity
Data not available.
Description
GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic ß-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
Endotoxin Levels
< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]
31
Molecular Weight
3.3 kDa
mRNA RefSeq
NM_002054.4
Protein RefSeq
NP_002045.1
Protein Sequence
HAEGTFTSDV SSYLEGQAAK EFIAWLVKGR G
Purity Confirmation
> 98% by SDS-PAGE & HPLC analyses
Synonyms
GLP1; GLP2; GRPP
Uniprot ID
P01275

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1000ug
Available: In stock
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