IL-28B

Item no.	RLT-M10-039
Manufacturer	ReliaTech
Amount	20ug
Category	Neuroscience Neural Transcription Factors Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Interferon lambda-3, IFN-lambda-3, Interleukin-28B, IL-28B, Ifnl3, Il28, Il28b
Available
NCBI Gene ID	338374
Uniprot	Q8CGK6
Biological Activity	The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 30 ng/ml, corresponding to a specific activity of > 3.3 × 104 IU/mg.
Buffer	PBS
Description	IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	174
Molecular Weight	19.6 kDa
mRNA RefSeq	NM_177396.1
Protein RefSeq	NP_796370.1
Protein Sequence	DPVPRATRLP VEAKDCHIAQ FKSLSPKELQ AFKKAKGAIE KRLLEKDMRC SSHLISRAWD LKQLQVQERP KALQAEVALT LKVWENINDS ALTTILGQPL HTLSHIHSQL QTCTQLQATA EPKPPSRRLS RWLHRLQEAQ SKETPGCLED SVTSNLFQLL LRDLKCVASG DQCV
Purity Confirmation	> 97% by SDS-PAGE & HPLC analyses
Reconstitution	It is recommended to reconstitute the lyophilized IL-28B in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability And Storage	Lyophilized IL-28B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C.
Synonyms	Interferon lambda-3, IFN-lambda-3, Interleukin-28B, IL-28B, Ifnl3, Il28, Il28b
Uniprot ID	Q8CGK6

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 20ug

available

Delivery expected until 11/20/2025

Express Delivery: Save 24 days

Compare

Add to wishlist

Get an offer