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FGF acidic

FGF acidic

Item no.	RLT-M10-045
Manufacturer	ReliaTech
Amount	50ug
Category	Oncology Neuroscience Metabolism Regulation of Appetite Neural Signaling Neural Adhesion Molecules By Cell Type Carcinoma Glioma Hematology Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines By Organ Bladder Cancer
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	HBGF-1, aFGF, acidic fibroblast growth factor, fibroblast growth factor 1 (acidic), heparin-binding growth factor 1
Available
NCBI Gene ID	14164
Uniprot	P61148
Biological Activity	Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is = 0.5 ng/ml (= 2 x 106 units/mg). Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is = 0.2 ng/ml in the presence of 10 µg/ml heparin (= 5 x 106 units/mg)
Description	FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant mouse FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	141
Molecular Weight	15.9 kDa
mRNA RefSeq	NM_010197.3
Protein RefSeq	NP_034327.1
Protein Sequence	MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	HBGF-1; aFGF; acidic fibroblast growth factor; fibroblast growth factor 1 (acidic); heparin-binding growth factor 1
Uniprot ID	P61148

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Delivery expected until 8/21/2025

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