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Midkine

Midkine

Item no.	RLT-M10-095
Manufacturer	ReliaTech
Amount	20ug
Category	Oncology Neuroscience Neural Signaling By Cell Type Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Mdk, MK, Mek
Available
NCBI Gene ID	17242
Uniprot	P12025
Biological Activity	Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml.
Description	Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant murine Midkine is a 13.4 kDa protein containing 121 amino acid residues including five intra-molecular disulfide bonds.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	120
Molecular Weight	13.3 kDa
mRNA RefSeq	NM_010784.4
Protein RefSeq	NP_034914.1
Protein Sequence	VAKKKEKVKK GSECSEWTWG PCTPSSKDCG MGFREGTCGA QTQRVHCKVP CNWKKEFGAD CKYKFESWGA CDGSTGTKAR QGTLKKARYN AQCQETIRVT KPCTSKTKSK TKAKKGKGKD
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	Mdk; MK; Mek
Uniprot ID	P12025

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20ug

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Delivery expected until 8/21/2025

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