Comparison

IL-11 European Partner

Item no. RLT-M10-118
Manufacturer ReliaTech
Amount 10ug
Category
Type Cytokines and Growth Factors
Format Lyophilized
Specific against Mouse (Murine, Mus musculus)
Host E.coli
ECLASS 10.1 42030690
ECLASS 11.0 42030690
UNSPSC 12352202
Alias Il11, IL-11
Available
NCBI Gene ID
16156
Uniprot
P47873
Biological Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is = 2.0 ng/ml, corresponding to a specific activity of = 5 x 105 units/mg.
Description
IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.
Endotoxin Levels
< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]
179
Molecular Weight
19.1 kDa
mRNA RefSeq
NM_008350
Protein RefSeq
NP_032376.1
Protein Sequence
MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Purity Confirmation
> 98% by SDS-PAGE & HPLC analyses
Synonyms
Il11; IL-11
Uniprot ID
P47873

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10ug
Available: In stock
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