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Rat Anti-Mouse Ly-6A/E-BIOT

Rat Anti-Mouse Ly-6A/E-BIOT

Item no.	SOBI-1755-08
Manufacturer	SouthernBiotech
Amount	0.5 mg
Category	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, FC, IP, IHC
Clone	D7
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a
Conjugate/Tag	Biotin
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Sca-1
Shipping Condition	Room temperature
Available
Manufacturer - Category	Primary Antibodies
Country of Origin	USA
Shipping Temperature	Ambient Temperature
Storage Conditions	2-8°C
Volume	1.0 mL
Product description	Ly-6A/E, also known as Sca-1, is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. In the periphery, Ly-6A/E exhibits a pattern of expression which is based on differences between the two allotypes. Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Ly-6A/E+ resting peripheral lymphocytes whereas Ly-6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Ly-6A/E+ lymphocytes. The expression of Ly-6A/E is dramatically upregulated in all strains upon cellular activation. Studies with the monoclonal antibody D7 suggest that Ly-6A/E may be involved in B and T lymphocyte responses and it appears that the antigen may be required for T-cell receptor-mediated T-cell activation.
Animal Ingredients	Purified rat immunoglobulins
Applications	FC, IHC-FS, IHC-PS, IP, WB
Concentration	0.5 mg/mL
Clonality	Monoclonal
Immunogen	IL-2 dependent mouse (C57BL/6) cytotoxic T cell line CTL-L
Manufacturer - Specificity	Ly-6A/E
Reactivity	Mouse Ly-6A/E

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

SOBI-1755-08-datasheet.pdf

SOBI-1755-08-safety-datasheet.pdf