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EGFR/ErbB-2/ErbB-4 inhibitor-2

EGFR/ErbB-2/ErbB-4 inhibitor-2

Item no.	TMO-T21954-2mg
Manufacturer	TargetMol
CASRN	179248-61-4
Amount	2 mg
Specific against	other
Smiles	COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC
Alias	EGFR/ErbB2 Inhibitor
Shipping condition	Cool pack
Available
Manufacturer - Targets	Apoptosis
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	742, 86
Description	Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM), exhibits an IC50 value of 3.38 μM against human dermal fibroblasts (HDF) and binds to Heat shock protein 90 (Hsp90) with a dissociation constant (Kd) of 3.86 μM, demonstrating its apoptosis-inducing capabilities [1].
Pathways	Apoptosis

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