CEA, Human (Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, Carcinoembryonic Antigen, CEA, Meconium Antigen 100, CD66e, CEACAM5)

Molecular Biology / MB-Cancer Markers

-20°C

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.

Source:
CEA, from human colon adenocarcinoma cell line.

Applications:
Suitable to be used as a single analyte standard or control. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.