Sox 2, Recombinant, Human (SOX2, SOX-2, Sex Determining Region Y-box 2, SRY (Sex Determining Region Y) Box 2, ANOP3, MCOPS3, MGC2413, Transcription Factor SOX2)

Blue Ice

23, 1

Supplied as a liquid in 20mM Tris HCl, pH 8.0, 200mM sodium chloride, 2mM DTT, 40% glycerol

SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. This Protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Recombinant human SOX2 protein was expressed in E. coli.

Recombinant corresponding to aa1-200 of human SOX2, expressed in E. coli.

Amino Acid Sequence:
MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY
PQHPGLNAHG AAQMQPMHRY LEHHHHHH

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.