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rAAV-hSyn-hM4D(Gi)-P2A-mCherry (AAV2/B10)

rAAV-hSyn-hM4D(Gi)-P2A-mCherry (AAV2/B10)

Item no.	BC-2655-AAV2/B10-2.0e12vg/ml-100ul
Manufacturer	Brain Case
Amount	100 ul (Titer: ≥2.0e+12 vg/ml)
Category	Viral Expression Adeno-Associated Virus Expression
Type	Vector
Certificate	GMP certified, ISO 9001:2015 Certified
Specific against	other
Dry ice	Yes
ECLASS 10.1	32160414
ECLASS 11.0	32160414
UNSPSC	41106600
Shipping Condition	Dry ice
Available
Manufacturer - Category	Chemical Genetics / Inhibition
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C
Serotype	AAV2/B10
Titer	≥2.0e+12 vg/ml
Promoter information	hSyn
Functional gene	hM4D(Gi)
Fluorescent marker	mCherry
Common serotype	AAV/Retro
Description	hM4Di is an engineered receptor (DREADD) derived from the human muscarinic acetylcholine receptor M4 (hM4D) that responds only to CNO and is no longer activated by acetylcholine. In certain neurons, CNO binding to hM4D activates Gi protein-coupled inward potassium channels (GIRK), leading to cell membrane hyperpolarization and inhibition of neuronal action potential firing.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul (Titer: ≥2.0e+12 vg/ml)

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