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Biotinylated Human Cystine/glutamate transporter (SLC7A11) Nanodisc (XCT-HM10NB)

Biotinylated Human Cystine/glutamate transporter (SLC7A11) Nanodisc (XCT-HM10NB)

Item no.	XCT-HM10NB-100UG
Manufacturer	KactusBio
Amount	100 ug
Category	Oncology By Cell Type
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	HIS
Dry ice	Yes
Sequence	Met1-Leu501
Alias	Cystine/glutamate transporter,xCT,SLC7A11,CCBR1
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	Cystine/glutamate transporter (SLC7A11)
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 68.4 kDa.
Description	Recombinant Biotinylated Human Cystine/glutamate transporter (SLC7A11) Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Leu501.
Background	Solute Carrier Family 7 Member 11 (SLC7A11, also known as xCT) is the functional subunit of the Xc- system, an anionic L-cystine/L-glutamate antiporter expressed on the cell surface. SLC7A11 expression is significantly upregulated in several types of cancers in which it can inhibit ferroptosis and favor cancer cell proliferation, invasion and chemoresistance. SLC7A11 expression is also increased in ovarian cancer tissues, suggesting a possible role of this protein as a therapeutic target.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS, 200mM L-Arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Biotinylated	yes

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

XCT-HM10NB-100UG-datasheet.pdf

XCT-HM10NB-100UG-safety-datasheet.pdf