Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody

Lymphoid Enhancer Binding Factor 1 (LEF1)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

PBS containing 0.09% sodium azide.

LEF1

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Mouse and Rat LEF1.