Centromere Protein A (CENPA) Antibody

Centromere Protein A (CENPA)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4) 2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].

PBS containing 0.09% sodium azide.

This product is for research use only.

CENPA_HUMAN