Eukaryotic Translation Initiation Factor 3 Subunit G (EIF3G) Antibody

Eukaryotic Translation Initiation Factor 3 Subunit G (EIF3G)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.

PBS containing 0.09% sodium azide.

EIF3G

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Mouse, Rat, Cow, Zebrafish and Xenopus EIF3G.