FK506 Binding Protein 1A (FKBP1A) Antibody

FK506 Binding Protein 1A (FKBP1A)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

PBS containing 0.09% sodium azide.

This product is for research use only.

FKB1A_HUMAN