Uroplakin-1a (UPK1A) Antibody

Uroplakin-1a (UPK1A)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.

PBS containing 0.09% sodium azide.

UPK1A

Purified through a protein A column, followed by peptide affinity purification.