Sirtuin 1 (SIRT1) Antibody

Sirtuin 1 (SIRT1)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

SIRT1 Antibody is a Rabbit Polyclonal antibody against SIRT1. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.

SIRT1

Purified by affinity chromatography.