E3 Ubiquitin-Protein Ligase Parkin (PRKN) Antibody

E3 Ubiquitin-Protein Ligase Parkin (PRKN)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

PRKN Antibody is a Rabbit Polyclonal antibody against PRKN. The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.

PRKN

Purified by affinity chromatography.

168600