Integrin Alpha-L (ITGAL) Antibody

Integrin Alpha-L (ITGAL)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

ITGAL Antibody is a Rabbit Polyclonal antibody against ITGAL. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.

ITGAL

Purified by affinity chromatography.