Integrin Alpha IIb / CD41 (ITGA2B) Antibody

Integrin Alpha IIb / CD41 (ITGA2B)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

ITGA2B Antibody is a Rabbit Polyclonal antibody against ITGA2B. ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

ITGA2B

Purified by affinity chromatography.