Histone Deacetylase 5 (HDAC5) Antibody

Primary Antibodies

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

HDAC5 Antibody is a Rabbit Polyclonal antibody against HDAC5. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

HDAC5

Purified by affinity chromatography.