Cytosolic Beta-Glucosidase (GBA3) Antibody

Cytosolic Beta-Glucosidase (GBA3)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).

PBS containing 0.09% sodium azide.

GBA3

Purified through a protein A column, followed by peptide affinity purification.