U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) Antibody

U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq].

PBS containing 0.09% sodium azide.

U2AF2

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Mouse U2AF2.