Nucleus Accumbens-Associated Protein 2 (NACC2) Antibody

Nucleus Accumbens-Associated Protein 2 (NACC2)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

PBS containing 0.09% sodium azide.

This product is for research use only.

NACC2_HUMAN