Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) Antibody

Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

PBS containing 0.09% sodium azide.

ARHGEF11

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Rat ARHGEF11.