Defensin Beta 121 (DEFB121) Antibody

Defensin Beta 121 (DEFB121)

DEFB121 Antibody is a Rabbit Polyclonal antibody against DEFB121. ?-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ?-defensins are developmentally regulated. The family of ?-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ?-defensins also are involved in sperm maturation and capacitation. ?-defensin 121 is a 76 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. While expressed at low levels in testis, ?-defensin 121 is abundantly expressed in epididymal caput and corpus and, unlike other ?-defensins, it does not appear to be regulated by androgens.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

DEFB121

Purified by affinity chromatography.